Eye Movements to Natural Images as a Function of Sex and Personality

Women and men are different. As humans are highly visual animals, these differences should be reflected in the pattern of eye movements they make when interacting with the world. We examined fixation distributions of 52 women and men while viewing 80 natural images and found systematic differences in their spatial and temporal characteristics. The most striking of these was that women looked away and usually below many objects of interest, particularly when rating images in terms of their potency. We also found reliable differences correlated with the images ’ semantic content, the observers’ personality, and how the images were semantically evaluated. Information theoretic techniques showed that many of these differences increased with viewing time. These effects were not small: the fixations to a single action or romance film image allow the classification of the sex of an observer with 64 % accuracy. While men and women may live in the same environment, what they see in this environment is reliably different. Our findings have important implications for both past and future eye movement research while confirming the significant role individual differences play in visual attention

Fatigue interventions in long term, physical health conditions: A scoping review of systematic reviews.

OBJECTIVE: Fatigue is prominent across many long term physical health conditions. This scoping review aimed to map the fatigue intervention literature, to ascertain if certain interventions may be effective across conditions, and if novel interventions tested in specific long term conditions may be promising for other conditions. METHODS: Scoping review methodological frameworks were used. Electronic bibliographic databases were searched (inception to November 2016) for systematic reviews of fatigue interventions in long term conditions. Inclusion criteria were: long term physical health condition; review focus on fatigue management; objective and systematic review process; primary review outcome is fatigue. Articles focussing on surgical interventions or treatments thought to trigger fatigue were excluded. A narrative synthesis was performed. RESULTS: Of 115 full texts screened, 52 reviews were included. Interventions were categorised as pharmacological and non-pharmacological (exercise, psychological/behavioural and complementary medicine). Pharmacological interventions did not consistently demonstrate benefit, except for anti-TNFs and methylphenidate which may be effective at reducing fatigue. Non-pharmacological interventions such as graded exercise and fatigue-specific psychological interventions may be effective, but heterogeneous intervention components limit conclusions. 'Complementary medicine' interventions (e.g. Chinese herbal medicines) showed promise, but the possibility of publication bias must be considered. CONCLUSIONS: Further research is necessary to inform clinical practice. The reported effectiveness of some interventions across inflammatory health conditions, such as anti-TNFs, aerobic exercise, and psychologically based approaches such as CBT, highlights a potential transdiagnostic avenue for fatigue management. More novel strategies that may be worth exploring include expressive writing and mindfulness, although the mechanisms for these in relation to fatigue are unclear. More work is needed to identify transdiagnostic mechanisms of fatigue and to design interventions based on these

A “Learning Revolution”? Investigating Pedagogic Practices around Interactive Whiteboards in British Primary Classrooms

Interactive whiteboards have been rapidly introduced into all primary schools under UK Government initiatives. These large, touch-sensitive screens, which control a computer connected to a digital projector, seem to be the first type of educational technology particularly suited for whole-class teaching and learning. Strong claims are made for their value by manufacturers and policy makers, but there has been little research on how, if at all, they influence established pedagogic practices, communicative processes and educational goals. This study has been designed to examine this issue, using observations in primary (elementary) school classrooms. It is funded by the UK Economic and Social Research Council and builds on the authors’ previous research on ICT in educational dialogues and collaborative activities

Vaccinia extracellular virions enter cells by macropinocytosis and acid-activated membrane rupture

Double membrane-bound vaccinia extracellular virions actively promote their own macropinocytosis. This, followed by acid-induced rupture of the outer membrane in endocytic vesicles, exposes the inner membrane for fusion with the endocytic membrane and release into the cytosol

Which behavioural and exercise interventions targeting fatigue show the most promise in multiple sclerosis? A systematic review with narrative synthesis and meta-analysis

Fatigue is a common and highly debilitating symptom of multiple sclerosis (MS). This meta-analytic systematic review with detailed narrative synthesis examined randomised-controlled (RCTs) and controlled trials of behavioural and exercise interventions targeting fatigue in adults with MS to assess which treatments offer the most promise in reducing fatigue severity/impact. Medline, EMBASE and PsycInfo electronic databases, amongst others, were searched through to August 2018. Thirty-four trials (12 exercise, 16 behavioural and 6 combined; n = 2,434 participants) met inclusion criteria. Data from 31 studies (n = 1,991 participants) contributed to the meta-analysis. Risk of bias (using the Cochrane tool) and study quality (GRADE) were assessed. The pooled (SMD) end-of-treatment effects on self-reported fatigue were: exercise interventions (n = 13) -.84 (95% CI -1.20 to -.47); behavioural interventions (n = 16) -.37 (95% CI -.53 to -.22); combined interventions (n = 5) -.16 (95% CI: -.36 to .04). Heterogeneity was high overall. Study quality was very low for exercise interventions and moderate for behavioural and combined interventions. Considering health care professional time, subgroup results suggest web-based cognitive behavioural therapy for fatigue, balance and/or multicomponent exercise interventions may be the cost-efficient therapies. These need testing in large RCTs with long-term follow-up to help define an implementable fatigue management pathway in MS.MS Society, U

Complete Set of Polarization Transfer Observables for the 12C(p,n)^{12}{\rm C}(p,n) Reaction at 296 MeV and 0∘^{\circ}

A complete set of polarization transfer observables has been measured for the $^{12}{\rm C}(p,n)$ reaction at $T_p=296 {\rm MeV}$ and $\theta_{\rm lab}=0^{\circ}$. The total spin transfer $\Sigma(0^{\circ})$ and the observable $f_1$ deduced from the measured polarization transfer observables indicate that the spin--dipole resonance at $E_x \simeq 7 {\rm MeV}$ has greater $2^-$ strength than $1^-$ strength, which is consistent with recent experimental and theoretical studies. The results also indicate a predominance of the spin-flip and unnatural-parity transition strength in the continuum. The exchange tensor interaction at a large momentum transfer of $Q \simeq 3.6 {\rm fm}^{-1}$ is discussed.Comment: 4 pages, 4 figure